KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
17.27
Human Site:
S834
Identified Species:
31.67
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S834
L
E
N
T
T
I
R
S
E
I
S
P
E
G
E
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S834
L
E
N
T
T
I
R
S
E
I
F
P
E
G
E
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S834
L
E
N
T
T
I
R
S
D
I
S
P
E
G
E
Dog
Lupus familis
XP_543184
1286
146207
S862
L
E
N
T
A
I
R
S
E
I
S
P
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
S786
L
E
N
T
S
F
K
S
E
V
Y
A
E
E
E
Rat
Rattus norvegicus
NP_001099552
648
74414
P247
K
R
N
P
R
D
R
P
S
V
N
S
I
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
V463
K
P
Q
S
R
K
N
V
V
K
E
E
E
Y
R
Chicken
Gallus gallus
XP_420401
1281
145243
S854
D
V
I
N
E
F
P
S
G
Q
L
Y
L
L
Y
Frog
Xenopus laevis
Q7ZZC8
944
104521
H543
L
A
C
G
L
N
E
H
N
K
L
G
L
N
Q
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
I296
H
G
R
P
G
G
W
I
T
S
T
R
T
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
K690
S
V
E
A
N
R
K
K
W
G
A
P
G
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
A205
A
M
K
P
A
F
K
A
F
D
M
Q
G
L
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
Y457
P
F
H
R
A
Q
T
Y
S
S
A
P
A
E
S
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
93.3
93.3
86.6
N.A.
53.3
20
N.A.
6.6
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
100
86.6
N.A.
73.3
33.3
N.A.
13.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
24
0
0
8
0
0
16
8
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
39
8
0
8
0
8
0
31
0
8
8
47
16
47
% E
% Phe:
0
8
0
0
0
24
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
8
0
8
8
8
0
0
8
8
0
8
16
24
8
% G
% His:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
31
0
8
0
31
0
0
8
0
8
% I
% Lys:
16
0
8
0
0
8
24
8
0
16
0
0
0
8
0
% K
% Leu:
47
0
0
0
8
0
0
0
0
0
16
0
16
24
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
47
8
8
8
8
0
8
0
8
0
0
16
0
% N
% Pro:
8
8
0
24
0
0
8
8
0
0
0
47
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
8
0
8
0
0
8
% Q
% Arg:
0
8
8
8
16
8
39
0
0
0
0
8
0
8
8
% R
% Ser:
8
0
0
8
8
0
0
47
16
16
24
8
0
0
8
% S
% Thr:
0
0
0
39
24
0
8
0
8
0
8
0
8
0
8
% T
% Val:
0
16
0
0
0
0
0
8
8
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _